01 / What it is
KPV is a 3-residue peptide corresponding to the C-terminal tail of alpha-MSH (Lys-Pro-Val). It is studied for anti-inflammatory signaling without the pigmentation signaling of the full MSH molecule.
Research use onlySpecification publishedQualified users only
Dermal, matrix & melanocortin research · AGX-08
KPV
The α-MSH-derived tripeptide
$70
10 mg lyophilized vial$7.00/mg · research use only
Research use only · no human or veterinary use, consumption, administration, diagnosis, treatment, prevention, cosmetic use, or food use. Sold to qualified laboratory and analytical users.
02 / Mechanism in the literature
KPV is associated with downregulation of pro-inflammatory pathways such as NF-κB in research models, delivering the anti-inflammatory portion of alpha-MSH's activity in a compact tripeptide.
03 / Research context
KPV appears in inflammation, gut-barrier, and dermal research literature as a small anti-inflammatory peptide.
Listed format10 mg lyophilized vial
SequenceLys-Pro-Val
Molecular formulaC16H30N4O4
Molecular weight342 g/mol
Catalogue referenceAGX-08
Listed price$70
PathwayNF-κB / inflammation
04 / Common questions
What is KPV derived from?
The final three amino acids of alpha-melanocyte-stimulating hormone (α-MSH), which carry much of its anti-inflammatory signaling.
Does it affect pigmentation like MSH?
Research indicates the KPV fragment retains anti-inflammatory activity without the melanocortin pigmentation signaling of full α-MSH.