01 / What it is
IGF-1 LR3 (Long R3 IGF-1) is an 83-residue analog of insulin-like growth factor 1, engineered for greatly extended activity. It is a cornerstone compound in cellular-growth research.
Research use onlySpecification publishedQualified users only
Endocrine & growth-factor research · AGX-09
IGF-1 LR3
Long-acting growth-factor research
$95
1 mg lyophilized vial$95.00/mg · research use only
Research use only · no human or veterinary use, consumption, administration, diagnosis, treatment, prevention, cosmetic use, or food use. Sold to qualified laboratory and analytical users.
02 / Mechanism in the literature
The 'Long R3' modifications reduce its binding to IGF-binding proteins, leaving more of the molecule free and active. In research models it signals through the IGF-1 receptor to influence cell proliferation and protein synthesis.
03 / Research context
IGF-1 LR3 is studied in muscle-cell, tissue-growth, and cell-culture literature as a potent, long-acting growth-factor analog.
Listed format1 mg lyophilized vial
Sequence83-residue IGF-1 analog
Molecular formulaC400H625N111O115S9
Molecular weight9118 g/mol
Catalogue referenceAGX-09
Listed price$95
04 / Common questions
Why 'Long R3'?
The name reflects two engineering changes — a longer N-terminal extension and an arginine substitution at position 3 — that extend its half-life.
How does it compare to native IGF-1?
Because it evades binding proteins, research reports describe it as substantially longer-acting than native IGF-1.